Thiamine (Vitamin B1)
Of 9,912 on-market thiamine (vitamin b1) products in the January 2026 DSLD dump, the median declared dose is 5 mg, and 73.5% list Thiamine Hydrochloride (Thiamine HCl) as the primary form.
Form share
Of 7,542 products with an identifiable primary form, here is the share held by each form of Thiamine (Vitamin B1) on the market today.
Embed this chart
Free to embed on your site or article — attribution and a link back are built into the frame.
| Form | Quality tier | n | Share |
|---|---|---|---|
| Thiamine Hydrochloride (Thiamine HCl) | Tier 1 | 5,547 | 73.5% |
| Thiamine Mononitrate | Tier 1 | 1,995 | 26.5% |
Forms we recognize but found no primary-form products for in this release: Benfotiamine (fat-soluble synthetic prodrug).
Form share over time
Entry-year breakdown of the top forms, 2012–2025.
Dose distribution
Deciles of declared dose per serving (mg), among 9,712 products with a disclosed amount, against the RDA of 1.2.
Embed this chart
Free to embed on your site or article — attribution and a link back are built into the frame.
- 98.5% of products fall below the fairy-dust threshold (120 mg, 20% of the studied low dose).
- 0.3% of products don't disclose an amount because Thiamine (Vitamin B1) is declared inside a proprietary blend.
Where does your dose rank?
Enter a per-serving dose (mg) to see exactly how it compares to the 9,706 on-market thiamine (vitamin b1) products with a disclosed amount. The chart above groups doses into deciles; this looks up the exact percentile for one number.
By dosage form
By target group
Top brands
Search interest over time
How often people search for thiamine (vitamin b1) on Google, US only, the last 5 years. This is public interest, not DSLD label data — a spike here doesn't necessarily line up with anything on this page, and Google's own index (100 = that term's peak popularity in the chosen window) is relative, not an absolute search-volume count.
Or see this search directly on trends.google.com.
Forms explained
Elemental fraction: 78.7% (thiamine cation MW 265.36 / thiamine HCl MW 337.26 (both confirmed PubChem formulas))
Both HCl and mononitrate are salts of the same thiamine cation and both are GRAS vitamin sources, so they are treated as equivalent on chemical grounds; no human head-to-head bioavailability trial was located. HCl's higher water solubility is used in liquid/injectable products.
Source: 21 CFR 184.1875 (thiamine hydrochloride); 21 CFR 184.1878 (thiamine mononitrate). The EFSA opinions PMC12035548/PMC11979709 are animal-feed authorisation opinions, not human bioavailability evidence.
Elemental fraction: 81.1% (thiamine cation MW 265.36 / thiamine mononitrate MW 327.36 (confirmed PubChem formula))
Same rationale as HCl -- a salt of the same thiamine cation, treated as equivalent on chemical grounds (no human head-to-head trial located); preferred for fortification for stability (HCl is hygroscopic), not for superior bioavailability.
Source: 21 CFR 184.1875 (thiamine hydrochloride); 21 CFR 184.1878 (thiamine mononitrate)
Early trials suggested neuropathy-symptom benefit, but longer/larger trials (BOND 12-month, 24-month T1D) found no significant benefit on nerve function despite good tolerability -- superior-bioavailability claims are not settled.
Source: Stracke H et al. 2008 (BENDIP), Exp Clin Endocrinol Diabetes 116(10):600-5, PMID 18473286; Fraser DA et al. 2012, Diabetes Care 35(5):1095-7, PMID 22446172 (24-month T1D, n=67); Ziegler D et al. 2026 (BOND), BMJ Open Diabetes Res Care 14(1):e005773, PMID 41571333
Reference values
- RDA (adult): 1.2 mg — 1.2mg (men); 1.1mg (women), ages 19+
- Tolerable Upper Intake Level (adult): not established — Not established -- data on adverse effects insufficient to set a UL; no observed toxicity from oral thiamine even at high doses
- Studied clinical dose range: 600–1800 mg
- Bager P et al. 2021, Aliment Pharmacol Ther 53(1):79-86, PMID 33210299 -- crossover RCT (n=40), high-dose oral thiamine HCl significantly reduced fatigue scores vs placebo (mean reduction 4.5 points vs +0.75 for placebo, p=0.0003) in quiescent IBD patients.
- Note: No DFE-style equivalency system applies to thiamine. The 600-1800mg studied range is a research dose, not a label safety limit -- no UL is established.