Glucosamine Sulfate
Glucosamine Sulfate is a tier 1 form of Glucosamine, used in 1,103 on-market products .
1,103
on-market products
tier 1
quality tier
n/a
elemental fraction
Why this tier: The positive long-term European RCTs showing both symptomatic AND structural (joint-space) benefit used glucosamine sulfate specifically (largely a particular pharmaceutical-grade "Rotta" preparation); a 2005 Cochrane review found benefit mainly in trials of the Rotta preparation, whereas non-Rotta preparations and trials with adequate allocation concealment showed no significant benefit.
Source: Reginster JY et al. 2001, Lancet 357(9252):251-256; Pavelka K et al. 2002, Arch Intern Med 162(18):2113-2123; Towheed TE et al., Cochrane Database Syst Rev 2005;(2):CD002946, PMID 15846645