Glycine
Of 1,579 on-market glycine products in the January 2026 DSLD dump, the median declared dose is 250 mg, and 100.0% list Glycine (unmodified free amino acid) as the primary form.
1,579
on-market products
250 mg
median dose
—
below RDA
—
above UL
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Form share
Of 1,573 products with an identifiable primary form, here is the share held by each form of Glycine on the market today.
| Form | Quality tier | n | Share |
|---|---|---|---|
| Glycine (unmodified free amino acid) | Tier 1 | 1,573 | 100.0% |
Form share over time
Entry-year breakdown of the top forms, 2012–2025.
Dose distribution
Deciles of declared dose per serving (mg), among 1,038 products with a disclosed amount.
- 71.4% of products fall below the fairy-dust threshold (600 mg, 20% of the studied low dose).
- 33.2% of products don't disclose an amount because Glycine is declared inside a proprietary blend.
By dosage form
By target group
Top brands
Forms explained
Glycine (unmodified free amino acid) Tier 1
The form used in essentially all clinical glycine literature; glycine is the only proteinogenic amino acid with no stereocenter, so "L-Glycine" is a labeling convention/synonym, not a distinct or superior form.
Source: Kawai N et al. 2012, Front Neurol 3:61, PMID 22529837
Reference values
- RDA (adult): not established — Non-essential/conditionally-essential amino acid; no IOM/NASEM RDA exists for individual non-essential amino acids (Elango R et al. 2023, PMC10334138).
- Tolerable Upper Intake Level (adult): not established — Not established -- no IOM/EFSA/FDA UL exists for glycine specifically.
- Studied clinical dose range: 3000–3000 mg
- Kawai N et al. 2012, Front Neurol 3:61, PMID 22529837 -- 3g oral glycine before bed under a sleep-restriction protocol improved subjective sleep quality, reduced next-day fatigue, and improved daytime cognitive performance vs placebo. [Study authors were employees of Ajinomoto, a major amino-acid manufacturer -- conflict-of- interest caveat worth carrying alongside this citation.]
- Note: Trimethylglycine (betaine/TMG) and Dimethylglycine (DMG), though sometimes marketed alongside glycine, are chemically and functionally DISTINCT compounds (methyl-donor/ osmolyte biology vs. glycine's neurotransmitter/collagen-precursor biology) -- modeled as separate compounds in this reference set, not as forms of glycine.