Supplement Label Index
Advertisement

Glycine

Of 1,579 on-market glycine products in the January 2026 DSLD dump, the median declared dose is 250 mg, and 100.0% list Glycine (unmodified free amino acid) as the primary form.

1,579
on-market products
250 mg
median dose
below RDA
above UL
Advertisement

Form share

Of 1,573 products with an identifiable primary form, here is the share held by each form of Glycine on the market today.

Glycine (unmodified free amino acid) 100.0%
FormQuality tiernShare
Glycine (unmodified free amino acid) Tier 1 1,573 100.0%

Form share over time

Entry-year breakdown of the top forms, 2012–2025.

Glycine (unmodified free amino acid)20122013201420152016201720182019202020212022202320242025

Dose distribution

Deciles of declared dose per serving (mg), among 1,038 products with a disclosed amount.

p10p20p30p40p50p60p70p80p90Fairy-dust
  • 71.4% of products fall below the fairy-dust threshold (600 mg, 20% of the studied low dose).
  • 33.2% of products don't disclose an amount because Glycine is declared inside a proprietary blend.

By dosage form

Powder 750 Capsule 427 Tablet or Pill 214 Other (e.g. tea bag) 85 Liquid 69 Lozenge 14 Softgel Capsule 10 Unknown 7

By target group

Adult (18 - 50 Years) 1,392 Gluten Free 706 Dairy Free 430 Sugar Free 273 Vegetarian 266 Women (not pregnant or lactating) 209 Vegan 164 Adult Male (18-50 Years) 149

Top brands

Forms explained

Glycine (unmodified free amino acid) Tier 1

The form used in essentially all clinical glycine literature; glycine is the only proteinogenic amino acid with no stereocenter, so "L-Glycine" is a labeling convention/synonym, not a distinct or superior form.

Source: Kawai N et al. 2012, Front Neurol 3:61, PMID 22529837

Reference values

  • RDA (adult): not established — Non-essential/conditionally-essential amino acid; no IOM/NASEM RDA exists for individual non-essential amino acids (Elango R et al. 2023, PMC10334138).
  • Tolerable Upper Intake Level (adult): not established — Not established -- no IOM/EFSA/FDA UL exists for glycine specifically.
  • Studied clinical dose range: 3000–3000 mg
  • Kawai N et al. 2012, Front Neurol 3:61, PMID 22529837 -- 3g oral glycine before bed under a sleep-restriction protocol improved subjective sleep quality, reduced next-day fatigue, and improved daytime cognitive performance vs placebo. [Study authors were employees of Ajinomoto, a major amino-acid manufacturer -- conflict-of- interest caveat worth carrying alongside this citation.]
  • Note: Trimethylglycine (betaine/TMG) and Dimethylglycine (DMG), though sometimes marketed alongside glycine, are chemically and functionally DISTINCT compounds (methyl-donor/ osmolyte biology vs. glycine's neurotransmitter/collagen-precursor biology) -- modeled as separate compounds in this reference set, not as forms of glycine.
Advertisement