Supplement Label Index

L-Glutamine Hydrochloride vs. Glutamine Alpha-Ketoglutarate

Among 231 on-market l-glutamine products with an identifiable primary form, 35.9% use L-Glutamine Hydrochloride (83 products) and 20.3% use Glutamine Alpha-Ketoglutarate (47).

L-Glutamine HydrochlorideGlutamine Alpha-Ketoglutarate
Quality tierUnratedUnrated
L-Glutamine by weight80.0%—
Share of market35.9%20.3%
On-market products8347
Median declared dose160 mg
middle half: 160–400
2,000 mg
middle half: 1,000–2,000
Most common brandsUniversal, GNC AMP Advanced Muscle Performance, MMUSAJustified Laboratories, PMD, Universal

Doses are declared per serving in mg. “By weight” is the share of the ingredient that is the nutrient itself (e.g. elemental magnesium in a magnesium salt).

Why L-Glutamine Hydrochloride is unrated

Same amino acid delivered as a salt; no human study comparing glutamine HCl with free glutamine was located.

Why Glutamine Alpha-Ketoglutarate is unrated

No head-to-head human bioavailability or efficacy comparison of this form was located in PubMed searches.

Tiers summarize published comparative bioavailability or outcome evidence for each form (see methodology). This page describes the market; it is not a recommendation to take either form. Talk to a clinician about what's right for you.

Other l-glutamine comparisons