Supplement Label Index

Arginine Alpha-Ketoglutarate (AAKG) vs. L-Arginine Pyroglutamate

Among 1,304 on-market l-arginine products with an identifiable primary form, 38.6% use Arginine Alpha-Ketoglutarate (AAKG) (503 products) and 4% use L-Arginine Pyroglutamate (52).

Arginine Alpha-Ketoglutarate (AAKG)L-Arginine Pyroglutamate
Quality tierUnratedUnrated
L-Arginine by weight70.5%57.4%
Share of market38.6%4%
On-market products50352
Median declared dose705 mg
middle half: 705–1,322.98
574 mg
middle half: 354.15–861
Most common brandsCellucor, Universal, BSNSource Naturals, Anabolic Warfare, Higher Nature

Doses are declared per serving in mg. “By weight” is the share of the ingredient that is the nutrient itself (e.g. elemental magnesium in a magnesium salt).

Why Arginine Alpha-Ketoglutarate (AAKG) is unrated

Tested in a controlled trial (4g three times daily x8 weeks improved 1RM bench press and Wingate peak power in 35 trained men) but only a time-release vs non-time-release comparison was run, not AAKG against other arginine forms.

Source: Campbell B et al. 2006, Nutrition 22(9):872-81, PMID 16928472

Why L-Arginine Pyroglutamate is unrated

No head-to-head human bioavailability or efficacy comparison of this form was located in PubMed searches.

Tiers summarize published comparative bioavailability or outcome evidence for each form (see methodology). This page describes the market; it is not a recommendation to take either form. Talk to a clinician about what's right for you.

Other l-arginine comparisons